Gentamicin-resistant Staphylococcus aureus
نویسندگان
چکیده
منابع مشابه
Aminoglycoside modification by gentamicin-resistant isolates of Staphylococcus aureus.
Three clinical isolates of Staphylococcus aureus, which were previously shown to contain a 50S plasmid conferring resistance to several aminoglycosides, were examined for modifying enzymes. Both the wild-type and heat-cured derivatives of the isolates were screened for acetyl-, adenylyl-, and phosphotransferase activities. The substrates were gentamicin, amikacin, and netilmicin; the results in...
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Vancomycin monotherapy of deep-seated staphylococcal infection may be associated with poor bacteriological response. We evaluated 24 unique patient isolates of methicillin-resistant Staphylococcus aureus (MRSA) for vancomycin-gentamicin synergism by determining time-kill curves for vancomycin at 10 micrograms/ml and gentamicin at 1 microgram/ml. Nine MRSA strains showed high-level gentamicin re...
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We report recurrent bacteremia due to mixed infection with two clonally derived isolates of Staphylococcus aureus in a patient with Sezary syndrome. The two isolates, one gentamicin resistant and methicillin susceptible and the other gentamicin susceptible and methicillin resistant, developed by the deletion of the mecA, ant(4')Ia, and aacA-aphD genes from a common gentamicin-resistant and meth...
متن کاملMechanisms of gentamicin resistance in Staphylococcus aureus.
Three clinical isolates of Staphylococcus aureus resistant to gentamicin and other aminoglycosides have been examined for antibiotic modifying enzymes. The strains contain a number of these enzymes, most of them similar to those commonly found in aminoglycoside-resistant gram-negative strains. All three strains (and a transductant derived from one of them) contain two enzymes mediating gentamic...
متن کاملMethicillin Resistant Staphylococcus aureus
Etiology Staphylococcus aureus is a Gram positive, coagulase positive coccus in the family Staphylococcaceae. Methicillin-resistant S. aureus (MRSA) strains are resistant to methicillin and essentially all other beta-lactam antibiotics. MRSA isolates are genetically heterogeneous. 1 Some strains, which are called epidemic strains; are more prevalent and can spread within or between hospitals an...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 1976
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/2.3.225